Pravachol
Brand name: Pravachol
Generic name: Pravastatin.
While using Pravacol: depletion of Coenzyme Q10 synthesis along with possible depletion of vitamin D may occur. If using this prescription drug to lower your cholesterol, you need: NutraMD High Cholesterol Essential Nutrients replacements - Buy Now!
Pravachol is a cholesterol-lowering drug that is prescribed along with a cholesterol-lowering diet if the blood cholesterol level is dangerously high and diet alone has not been able to lower it. High cholesterol can lead to heart problems. By lowering your cholesterol, Pravachol improves your chances of avoiding a heart attack, heart surgery, and death from heart disease. In people who already have hardening of the arteries, it slows progression of the disease and cuts the risk of acute attacks.
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Pravastatin is an oral drug for lowering cholesterol in the blood. It has been shown to reduce the occurrence of heart attacks, strokes and death caused by coronary heart disease. It belongs to a class of drugs called HMG-CoA reductase Inhibitors, commonly called "statins".
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References:
1.Bliznakov EG. Coenzyme Q10, Lipid-Lowering Drugs (Statins) and Cholesterol: A Present Day Pandora’s Box. Physcians should consider the potential for drug-nutrient depletion. JANA 2002; 5(3): 32-38.
2.De Pinieux G, Chariot P, et al. Lipid-lowering drugs and mitochondrial function: effects of HMG-CoA reductase inhibitors on serum ubiquinone and blood lactate/pyruvate ratio. Br J Clin Pharmacol 1996; 42: 333-37.
3.Mortensen SA, Leth A, et al. Dose-related Decrease of Serum Coenzyme Q10 During Treatment with HMG-CoA Reductase Inhibitors. Molec Aspests Med 1997; 18(suppl): s137-s144.
4.Ghirlanda G, Oradei A, et al. Evidence of Plasma CoQ10 Lowering Effect by HMG-CoA Reductase Inhibitors: A Double-Blind, Placebo-Controlled Study. J Clin Pharmacol 1993; 33:226-229.
5.Strey CH, Young JM, et al. Endothelium-ameliorating effects of statin therapy and coenzyme Q10 reductions in chronic heart failure. Atherosclerosis 2005; 179:201-206.
