Corgard
Brand name:Corgard
Generic name: Nadolol
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Corgard is used in the treatment of angina pectoris (chest pain, usually caused by lack of oxygen to the heart due to clogged arteries) and to reduce high blood pressure. When prescribed for high blood pressure, it is effective when used alone or in combination with other high blood pressure medications. Corgard is a type of drug known as a beta blocker. It decreases the force and rate of heart contractions, reducing the heart's demand for oxygen and lowering blood pressure.
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Nadolol is a beta-adrenergic receptor blocking agent that primarily blocks the action of the sympathetic nervous system on the heart. Nadolol reduces the heart rate and the force of contractions of the heart's muscle, thereby lowering blood pressure. Angina (heart pain) occurs when the heart's need for oxygen exceeds the supply of oxygen. By slowing the heart rate and decreasing the force of muscle contractions, nadolol reduces the demand of the heart's muscle for oxygen and thereby prevents angina.
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References:
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2. Urinary Loss of Thiamine is Increased by Low doses of Furosemide in Healthy Volunteers.
J Lab Clin Med 1999;134:238-43